Palosco (Bergamasque: ) is a comune (municipality) in the Province of Bergamo in the Italian region of Lombardy, located about east of Milan and about southeast of Bergamo. As of 31 December 2004, it had a population of 5,353 and an area of .
Palosco borders the following municipalities: Bolgare, Calcinate, Cividate al Piano, Martinengo, Mornico al Serio, Palazzolo sull'Oglio, Pontoglio, Telgate.
The surnames Paloschi y Palloschi are believed to be toponyms for Palosco (Palösch in