Paliseul (; ) is a municipality of Wallonia located in the province of Luxembourg, Belgium.
On 1 January 2007 the municipality, which covers 112.96 km<sup>2</sup>, had 5,055 inhabitants, giving a population density of 44.8 inhabitants per km<sup>2</sup>.
The municipality consists of the following districts: Carlsbourg, Fays-les-Veneurs, Framont, Maissin, Nollevaux, Offagne, Opont, and Paliseul. Other population centers include: Beth, Bour, Merny, Our, and Plainevaux.