Palazzolo Vercellese (Palasseu in Piedmontese) is a comune (municipality) in the Province of Vercelli in the Italian region Piedmont, located about northeast of Turin and about southwest of Vercelli. As of 31 December 2004, it had a population of 1,348 and an area of .
Palazzolo Vercellese borders the following municipalities: Camino, Fontanetto Po, Gabiano, and Trino.