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Protein phosphatase methylesterase-1

The enzyme protein phosphatase methylesterase-1 (EC 3.1.1.89, PME-1, PPME1; systematic name (phosphatase 2A protein)-leucine ester acylhydrolase catalyses the reaction

[phosphatase 2A protein]-leucine methyl ester + H<sub>2</sub>O [phosphatase 2A protein]-leucine + methanol

A key regulator of protein phosphatase 2A.

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