PHA-57378 is a drug related to the ibogalogs which acts as an agonist at serotonin 5-HT<sub>2</sub> receptors, having a binding affinity of 4.1 nM at the 5-HT<sub>2A</sub> subtype and 4.3 nM at 5-HT<sub>2C</sub>. It has anxiolytic effects in animal studies.