Oxbow is a hamlet and census-designated place (CDP) in the town of Antwerp, Jefferson County, New York, United States. As of the 2020 census, Oxbow had a population of 85.
It was founded in 1817 by Abraham Cooper, an ancestor of Ambassador Charles W. Yost. Located at Oxbow is the Dr. Abner Benton House (1819), listed on the National Register of Historic Places in 1984.
Oxbow is in northern Jefferson County, in the northern part of the town of Antwerp. It sits at the south end of a sharp bend in the Oswegatchie River at an altitude of . According to the United States Census Bureau, the CDP has a total area of , all land.
Oxbow is northeast of Watertown, the Jefferson county seat, and southwest of Gouverneur.
The school district is the Indian River Central School District.