Ottobiano is a comune (municipality) in the Province of Pavia in the Italian region Lombardy, located about southwest of Milan and about west of Pavia. As of 31 December 2004, it had a population of 1,168 and an area of .
Ottobiano borders the following municipalities: Ferrera Erbognone, Lomello, San Giorgio di Lomellina, Tromello, Valeggio.