Otoyol 52 (), abbreviated as O-52, Adana-à Âanlñurfa Otoyolu (), is a toll motorway in the regions of Mediterranean and Southeastern Anatolia in Turkey, connecting the cities Adana and à Âanlñurfa. The motorway is part of European route E90 and Asian Highway 84. The O-52 starts from the eastern terminus of The O-51, runs eastward through Osmaniye, Gaziantep and terminates east of à Âanlñurfa. The O-52 is currently the second longest Motorway in Turkey being only 5 km shorter than the O-4.
The highway sustained damage in the 2023 TurkeyâÂÂSyria earthquake.
Light blue indicates toll section of motorway.