is a town located in Hiyama Subprefecture, Hokkaido, Japan.
As of September 2016, the town has an estimated population of 3,925, and a density of 24 persons per km<sup>2</sup>. The total area is 162.55 km<sup>2</sup>.
Otobe is located on the western of the Oshima Peninsula and faces the Sea of Japan.
The name came from Ainu word that means "The river with a marsh in its estuary". This river is Hime River, which flows through the town.