Osino is a census-designated place (CDP) along the Humboldt River in central Elko County, Nevada, United States. As of the 2020 census, Osino had a population of 668.
Osino is located on Interstate 80 (Exit 310) on the northern foothills of two mountain ranges: the Elko Hills (on the south) and the Adobe Range (on the west). It is northeast of Elko and southwest of Wells.