Orpheus is an unincorporated community in Bloomfield Township, Jackson County, Ohio, United States.
It is located northeast of Oak Hill and east of Vega at the intersection of Orpheus-Keystone Road and Orpheus Road, at .
The Orpheus Post Office was established on September 15, 1888, and discontinued on September 14, 1907. Mail service is now handled through the Rempel branch.