Opiranserin (; developmental code name VVZ-149) is a selective and combined glycine GlyT2 transporter blocker ( = 0.86 üM), purine P2X<sub>3</sub> receptor antagonist ( = 0.87 üM), and serotonin 5-HT<sub>2A</sub> receptor antagonist ( = 1.3 üM) which is under development by Vivozon for the intravenous treatment of postoperative pain. As of April 2017, it is in phase II clinical trials for this indication. The of the drug was issued in 2017. Approved for post-operative pain management in South Korea in December of 2024.