Oggiona con Santo Stefano is a comune (municipality) in the Province of Varese in the Italian region Lombardy, located about northwest of Milan and about south of Varese. As of 31 December 2004, it had a population of 4,370 and an area of .
Oggiona con Santo Stefano borders the following municipalities: Carnago, Cassano Magnago, Cavaria con Premezzo, Jerago con Orago, Solbiate Arno.
It is served by Cavaria-Oggiona-Jerago railway station.