Odontarrhena lesbiaca, syn. Alyssum lesbiacum, is a species of flowering plant in the family Brassicaceae. It is native only to the East Aegean Islands, such as Lesbos, Rhodes or Samos.
The species was first described by Paléologos C. Candargy in 1897 under its current accepted binomial name.
The Latin specific epithet lesbiaca means "Lesbian", which references its native occurrence on the Greek island of Lesbos.