"Nothing Left to Lose" is a song by American artist Mat Kearney. It was released in May 2006 as the lead single from major-label debut of the same name. The song charted number 21 on the Billboard Hot Adult Contemporary Tracks and peaked on the Billboard Hot 100 at number 41 . The single was certified gold on November 6, 2007.
In 2007, the song was nominated for a Dove Award for Song of the Year at the 38th GMA Dove Awards.