Nong Prue (, ) is a district (amphoe) in the northeastern part of Kanchanaburi province, central Thailand.
The two subdistricts Nong Prue and Nong Pla Lai were split of from Bo Phloi district to establish the minor district (king amphoe) Nong Prue on 22 April 1992. A third subdistrict, Somdet Charoen, was later included in the new minor district as well. The minor district was upgraded to a full district on 11 October 1997.
Neighboring districts are (from the east clockwise) Lao Khwan, Bo Phloi, Si Sawat of Kanchanaburi province and Dan Chang of Suphanburi province.
The district is named after the Prue plant, Cyperus sp.
The district is divided into three subdistricts (tambons), which are further subdivided into 43 administrative villages (mubans).
As of December 2024 there are three municipal (thesaban) areas in the district: Somdet Charoen and Nong Pla Lai subdistrict municipalities (thesaban tambons) cover the whole subdistricts, Nong Prue subdistrict municipality covers parts of the same-named subdistrict.
The non-municipal areas are administered by one subdistrict administrative organization - SAO (ongkan borihan suan tambon - o bo toh).
Nong Prue district is served by two hospitals
In the district there are seven health-promoting hospitals in total.
There are thirty-six Theravada Buddhist temples in the district.
The Christians have three churches.