The Ninigret National Wildlife Refuge is a National Wildlife Refuge situated along the shore of Ninigret Pond. It is characterized by salt marshes, kettle ponds, freshwater wetlands, maritime shrub lands, and forests, and it is seasonally inhabited by over 250 species of birds. During the winter months, black ducks, Canada geese, and diving ducks are especially prominent on the pond, while various species of migrating raptors are also common. Wildlife refuge staff also maintain a piping plover nesting program.
The area was originally used for farming. During World War II, the United States Navy used it as Naval Auxiliary Air Station Charlestown, an auxiliary landing field. It was designated as a refuge in 1970 upon the transfer of of land to the United States Fish and Wildlife Service. Subsequent transfers and purchases increased the protected area to approximately .