Nikos Vafeas (; born 21 February 1997) is a Greek professional footballer who plays as a centre-back for Super League 2 club Kalamata.
On 29 June 2017, he signed a contract with Apollon Smyrnis.
On 23 January 2020, following his release from Apollon Smyrnis, he joined OFI on a two-and-a-half-year contract.
On 28 June 2021, Vafeas signed a contract with Ionikos.