Nikos Melissas (; born 24 February 1993) is a Greek professional footballer who plays as a goalkeeper for Super League club AEL.
On 10 August 2017, Melissas was given on loan to newly promoted side Lamia.
On 7 June 2018, his loan was extended by an additional year.
On 24 June 2019, he signed a new contract with PAOK, running until the summer of 2022.