Nikolas Mattheou (, born 7 May 1998 in Limassol) is a Cypriot professional footballer who plays as a winger for Karmiotissa.
Mattheou started from Apollon Limassol youth clubs, and he moved to PAOK youth clubs in 2014. On 1 June 2016, Mattheou signed a three-year contract with PAOK. He was an used substitute at the 2016âÂÂ17 Greek Football Cup final. On 23 June 2017, Mattheou was loaned to Anorthosis Famagusta. On 30 September 2017 he made his debut in 1âÂÂ1 draw, against AEK Larnaca. Mattheou replaced Giorgos Economides at the 88th minute, and made the assist to Demba Camara who tied the game at the 91st minute.
On 22 July 2019, Mattheou returned to his childhood club Apollon Limassol FC on a three-year contract. On 4 September, he was loaned out to Aris Limassol FC for the 2019âÂÂ20 season.