Nicholas Plastino (born February 20, 1986) is a Canadian-born Italian former professional ice hockey defenceman who last played with HC Pustertal Wölfe in the ICE Hockey League (ICEHL).
On July 7, 2017, Plastino agreed to a one-year contract with HC Ambrì-Piotta of the National League (NL).
Plastino competed at the 2010 and 2012 IIHF World Championships as a member of the Italy men's national ice hockey team.