Nicholson is an unincorporated community and census-designated place (CDP) in Pearl River County, Mississippi, United States. As of the 2020 census, its population was 2,833. Its ZIP code is 39463.
As of the 2020 United States census, there were 2,833 people, 1,265 households, and 764 families residing in the CDP.
It is in the Picayune School District, which operates Picayune Memorial High School.