Newcastle-under-Lyme railway station served the town of Newcastle-under-Lyme, in Staffordshire, England, between 1852 and 1964. It was a stop on the Stoke to Market Drayton Line.
The station was opened by the North Staffordshire Railway in 1852, on the line between and .
The station was located on King Street, opposite the Borough Arms Hotel. A small goods yard was located on Water Street.
The station was recommended for closure in the Beeching Report of 1963, along with Silverdale and Liverpool Road Halt. It was closed on 2 March 1964.
The station has been demolished and landscaped, but the parapet wall, part of the over bridge which is located across the Borough Arms Hotel, is extant.
The former trackbed north of the station has been built over, near to the former Hartshill tunnel and . The cutting has also been filled in and much of the trackbed forms part of Station Walks, a shared-use path used regularly by walkers and bikers.