Nevropoli Agrafon () is a former municipality in the Karditsa regional unit, Thessaly, Greece. Since the 2011 local government reform it is part of the municipality Lake Plastiras, of which it is a municipal unit. The municipal unit has an area of 105.184 km<sup>2</sup>. Population 2,362 (2021). The seat of the municipality was in Pezoula. The municipality's name derives from the ancient city of "Nevròpolis" of the Agrafa Mountains.