"Never Be the Same Again" is the lead single from the album Bulletproof Wallets by Ghostface Killah. The single features fellow Wu-Tang Clan member Raekwon and Carl Thomas. The single features a heavy R&B vibe, a departure from Ghost's normal output.
The song was later added to his greatest hits album Shaolin's Finest.
Described as a "sappy love song", "Never Be the Same Again" is a departure for Ghost's usual street-oriented output. The video shows Ghost and his girl, played by actress LisaRaye, in a courtroom with Judge Mills Lane presiding.