Nesploy () is a commune in the Loiret department in north-central France.
The river Bézonde goes through the commune limits. The commune itself is located in the Orléanais agricultural region. Nearby municipalities are Combreux, Montbarrois, Saint-Loup-des-Vignes, and Fréville-du-Gâtinais.
The area of this town has historically been located in the royal forest of the Duke of Orléans. Only one of four castles remain from the past.