Nathalie Sarles (; born 17 April 1962) is a French nurse and politician of the Democratic Movement (MoDem) who served as a member of the National Assembly from 2017 to 2022., representing the 5th constituency of the department of Loire.
Sarles was previously a nurse before becoming a councillor for Villerest commune.
In parliament, Sarles served on the Sustainable Development, Spatial and Regional Planning Committee.
She lost her seat in the second round of the 2022 French legislative election to Antoine Vermorel-Marques.
In 2020, Sarles went against the LREM parliamentary group's majority and abstained from an important vote on a much discussed security bill drafted by her colleagues Alice Thourot and Jean-Michel Fauvergue that helps, among other measures, curtail the filming of police forces.