N6-methyl-lysine oxidase () is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are N6-methyllysine, water, and oxygen. Its products are L-lysine, hydrogen peroxide and formaldehyde.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is N6-methyl-L-lysine:oxygen oxidoreductase (demethylating). Other names in common use include epsilon-alkyl-L-lysine:oxygen oxidoreductase, N6-methyllysine oxidase, epsilon-N-methyllysine demethylase, epsilon-alkyllysinase, and 6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating).