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N-succinylarginine dihydrolase

In enzymology, a N-succinylarginine dihydrolase () is an enzyme that catalyzes the chemical reaction

N<sub>2</sub>-succinyl-L-arginine + 2 H<sub>2</sub>O N<sub>2</sub>-succinyl-L-ornithine + 2 NH<sub>3</sub> + CO<sub>2</sub>

Thus, the two substrates of this enzyme are N2-succinyl-L-arginine and H<sub>2</sub>O, whereas its 3 products are N2-succinyl-L-ornithine, NH<sub>3</sub>, and CO<sub>2</sub>.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N2-succinyl-L-arginine iminohydrolase (decarboxylating). Other names in common use include N2-succinylarginine dihydrolase, arginine succinylhydrolase, SADH, AruB, AstB, and 2-N-succinyl-L-arginine iminohydrolase (decarboxylating). This enzyme participates in arginine and proline metabolism.

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