In enzymology, N-methylalanine dehydrogenase () is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are N-methyl-L-alanine, water, and oxidised nicotinamide adenine dinucleotide phosphate (NADP<sup>+</sup>). Its products are pyruvic acid, methylamine, reduced NADPH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH<sub>2</sub> group of donors with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is N-methyl-L-alanine:NADP<sup>+</sup> oxidoreductase (demethylating, deaminating).