In enzymology, a N-carbamoyl-D-amino acid hydrolase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are N-carbamoyl-D-amino acid and H<sub>2</sub>O, whereas its 3 products are D-amino acid, NH<sub>3</sub>, and CO<sub>2</sub>.
This enzyme belongs to the subfamily of hydrolases which act on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , and .