The enzyme N-acetylglucosamine-1-phosphodiester ñ-N-acetylglucosaminidase (EC 3.1.4.45) catalyzes the reaction
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is glycoprotein-N-acetyl-<small>D</small>-glucosaminyl-phospho-<small>D</small>-mannose N-acetyl-<small>D</small>-glucosaminylphosphohydrolase. Other names in common use include ñ-N-acetylglucosaminyl phosphodiesterase, lysosomal ñ-N-acetylglucosaminidase, phosphodiester glycosidase, ñ-N-acetyl-<small>D</small>-glucosamine-1-phosphodiester, N-acetylglucosaminidase, 2-acetamido-2-deoxy-ñ-<small>D</small>-glucose 1-phosphodiester, and acetamidodeoxyglucohydrolase.