The N-terminal peptide/fragment of proopiomelanocortin (NPP; N-POMC), also known as pro-ó-MSH, is a naturally occurring, endogenous metabolite of the polypeptide proopiomelanocortin (POMC).
N-POMC is also a precursor for ó1-MSH, ó2-MSH, and ó3-MSH, and can form them through proteolytic cleavage.
N-POMC is an adrenal growth factor.