Mytishchinsky District () is an administrative and municipal district (raion), one of the thirty-six in Moscow Oblast, Russia. It is located in the center of the oblast just north of the federal city of Moscow. The area of the district is . Its administrative center is the city of Mytishchi. As of the 2010 Census, the total population of the district was 203,393, with the population of Mytishchi accounting for 85.1% of that number.