Muyezersky District (; ) is an administrative district (raion), one of the fifteen in the Republic of Karelia, Russia. It is located in the west of the republic. The area of the district is . Its administrative center is the urban locality (an urban-type settlement) of Muyezersky. As of the 2010 Census, the total population of the district was 12,236, with the population of the administrative center accounting for 27.2% of that number.
Within the framework of administrative divisions, Muyezersky District is one of the fifteen in the Republic of Karelia and has administrative jurisdiction over one urban-type settlement (Muyezersky) and twenty-three rural localities. As a municipal division, the district is incorporated as Muyezersky Municipal District. The urban-type settlement of Muyezersky is incorporated into an urban settlement, while the twenty-three rural localities are incorporated into seven rural settlements within the municipal district. The urban-type settlement of Muyezersky serves as the administrative center of both the administrative and municipal district.