The multi-coloured tree frog or multi-coloured frog (Nyctimystes multicolor) is a species of frog in the subfamily Pelodryadinae. It is endemic to West Papua, Indonesia. It has been observed about 950 meters above sea level. Its natural habitats are subtropical or tropical moist lowland forests, subtropical or tropical moist montane forests, swamps, and freshwater marshes. It is threatened by habitat loss.