The Muisne River is a river of Ecuador that enters the Pacific Ocean in the Esmeraldas Province.
The Muisne River is the main river in CojimÃÂes sub-region of the ManabÃÂ mangroves ecoregion. It discharges into the Pacific. The low-keyed Muisne resort is in the northern part of the Ensenada de Mompiche, on a sand bar among the mangroves of the Muisne River estuary. It may be reached by ferry across the Muisne River from the small town of El Relleno.