Muhammadi-biy Qoshbegi was the grand vizier of the Emirate of Bukhara from 1872 until his death in 1889. Of Iranian Shia slave origin, he was the father of Muhammad Sharif-biy Inaq and grandfather of Astanaqul-biy Qoshbegi. After his death, he was succeeded by another Iranian Shia, Mulla Jan Mirza Sabzavari.