Muhammad Ramzan Hussain (Urdu: ), also known as Ramzan Sr., was a Pakistani footballer who played as a defender. He represented the Pakistan national team in their international debut in 1950, and the 1952 Asian Quadrangular Football Tournament.
Ramzan played for the Mohammedan Sporting Club in the 1950s. Ramzan also represented the Sindh football team in 1950, and later the Karachi football team at the National Football Championship.
In 1950, Ramzan was part of the Pakistan national football team which toured Iran and Iraq. Two years later, Ramzan represented the Pakistan national team at the 1952 Asian Quadrangular Football Tournament, held in Colombo, Ceylon. In the tournament, he featured as a starter in all the matches Pakistan played. The same year, he featured for Pakistan against the Iran national team during their tour to Pakistan.