Moyen-Mono is a prefecture located in the Plateaux Region of Togo. The prefecture covers 594.7 km<sup>2</sup>, with a population in 2022 of 90,505. The prefecture seat is located in Tohoun.
Cantons of Moyen-Mono include Tohoun, Kpékplémé, Tado, Saligbè, Ahassomé, and Katomé.