Moondyne Nature Reserve is a reserve located within the Avon Valley National Park, in the Avon Valley, Western Australia.
Considered and reviewed in 1979 and 1980, it was established in 1981.
A guide was published in 1984 as to the features within the reserve.
A trip into the reserve area in 2013, was considered to one of the events that contributed to the establishment of the Toodyaypedia project.