Sheikh Mohammed bin Khalifa bin Zayed Al Nahyan () is an Emirati politician. He is the son of the previous President of the United Arab Emirates, Khalifa bin Zayed Al Nahyan.
Sheikh Mohammed is the member of Executive Council of Abu Dhabi. He is also on the board of directors of Abu Dhabi Investment Authority
In 2009, he was appointed chairman of Abu Dhabi Retirement Pensions and Benefits Fund.