Gholamhossein Mohammadi (; born ), better known as Mohammad Mohammadi Golpayegani (), is an Iranian Shia Islamic cleric who has been the Chief of Staff of the Office of the Supreme Leader of Iran since 1989. He is also famous as "Hujjat al-Islam Golpayegani" was born in 1943 (1322 S.H.) in the city of Golpayegan, in Isfahan province.
His father, Abul Qasim Mohammadi Golpayegani, was well known as an Islamic scholar/commentator; he was also the Imam of Friday Prayer in Golpayegan, a city northwest of Isfahan. He was among the political warriors against Pahlavi, and also among the audience in the event of attack to Feyziyeh School. Mohammadi Golpayegani is a poet, too, and there have been published poems in his name in the press of Iran. "Persian Gulf" is regarded among his prominent poems that describes it according to his words. One of his sons married Boshra Khamenei, daughter of Iran's second Supreme Leader Ali Khamenei. Boshra and one of Mohammadi Golpayegani's grandchildren by the couple died during the assassination of Ali Khamenei in 2026.