As of 2003, the district had an estimated population of 29,682 and a density of 181.49 persons per km<sup>2</sup>. The total area was 163.55 km<sup>2</sup>.
On March 28, 2005 - the towns of Mitsugi and Mukaishima were merged into the expanded city of Onomichi. Mitsugi District was dissolved as a result of this merger.