Mithu Mukherjee is a former Indian actress who appeared in Hindi as well as Bengali cinema. She made her debut in a 1971 Bengali film Shesh Parba directed by Chitta Bose. She was catapulted to stardom after she had donned the role of Marjina in Dinen Gupta's Marjina Abdulla (1973) and sustained it with further roles in Bengali films such as Nishi Kanya (1973), Mouchak (1974), Swayamsiddha (1975), Hotel Snow Fox (1976), Bhagyachakra (1980) and Sandhi (1980). She made her Bollywood debut with Dulal Guha's Khaan Dost (1976). After her Dujane (1984) tanked at the box office, she took a sabbatical of seven years and returned to silver screen with Chandra Barot's hugely successful commercial drama Ashrita (1990).
Mukherjee made her debut in 1971 Bengali hit film Shesh Parba opposite Samit Bhanja, directed by Chitta Bose. She became known after portraying Marjina, a perspicacious maid of Ali Baba, in Dinen Gupta's Blockbuster Marjina Abdulla (1972) opposite Debraj Roy. She was then featured in Ashutosh Mukherjee's Nishikanya (1973) opposite Soumitra Chattopadhyay.
In 1974, she appeared in Arabinda Mukhopadhyay's Blockbuster Mouchak opposite Ranjit Mallick. The following year, she appeared in Sunil Bandopadhyay's Kabi opposite Debraj Roy for the second time which wasn't a commercial success. The movie Swayamsiddha opposite Ranjit Mallick, her last release of that year, was a box office success.
Her career faced a major setback when two of her high profile movies of 1976 - Hotel Snow Fox and Chander Kachhakachhi weren't commercially successful spite having Uttam Kumar in the lead.
She made her Bollywood debut with Dulal Guha's Khaan Dost (1976) opposite Shatrughan Sinha, but limited herself to Basu Chatterjee's films only. Mukherjee starred in Safed Jhoot (1977) opposite Vinod Mehra. Both her Bollywood movies as lead did not do well at the Box office.
In 1977, she played the first wife of Soumitra Chatterjee in Palash Bandopadhyay's Bengali hit Pratima. In 1978, she was only seen in two Hindi movies directed by Basu Chatterjee - Dillagi, where she was cast opposite Shatrughan Sinha, and Do Ladke Dono Kadke opposite Navin Nischol. Both films failed to propel her career in Bollywood further.
Throughout 1979 and 1980, she starred in Bengali family dramas like Bhagya Chakra, Bandhan and Sandhi, which achieved moderate success.
Her only release in 1981 was Bengali movie Father, where she played a deaf mute rape victim opposite Subhendu Chattopadhyay. In 1982, she acted in Dinen Gupta directed Oriya movie Jwain Pua opposite Uttam Mohanty, a remake of her Bengali film Mouchak.
In 1983, she appeared in Dujane that was a commercial failure. After a one song two scenes guest appearance in 1984 movie Prarthana, Mukherjee started shooting for her home production Ranga Bhanga Chand based on Pratibha Basu's novel of the same name in 1984. The following year, shooting stopped midway due to differences between Mukherjee and Gupta. The release was delayed by five years as the movie was left in the cans and later revived with Chandra Barot as director. At release Ranga Bhanga Chand was renamed Ashrita.
In 1990, Ashrita, in which Mukherjee starred opposite Kanwaljit Singh was very commercially successful. Ashrita was Mukherjee's final movie.