The Mitchigan River is a stream in the Upper Peninsula of the U.S. state of Michigan. It flows into the Fence River at in northeast Iron County in Mansfield Township. The Fence River is a tributary of the Michigamme River, which is itself a tributary to the Menominee River, flowing to Lake Michigan. The Mitchigan River has its source in the southeast corner of Baraga County at . It flows mostly southward along the boundary between Iron and Marquette counties, crossing briefly into western Marquette County.
Named tributaries from the mouth include: