The Mitchell River is a tributary of the Quesnel River, approximately long, near the eastern boundary of British Columbia, Canada. It originates in glaciers in the northern Columbia Mountains and flows generally southwest through Mitchell Lake into Quesnel Lake, and its water eventually travels down the Fraser River to the Pacific Ocean. Almost half of its course is flooded in natural lakes. Mitchell Lake, about long, is near the middle of the Mitchell River's course, and the river's lower are flooded by Quesnel Lake, although both bodies of water are natural.