The 1881 Mississippi gubernatorial election took place on November 8, 1881, in order to elect the Governor of Mississippi. Incumbent Governor John M. Stone ran for reelection to a second full term, but lost the Democratic nomination to Robert Lowry.
In the general election, Democratic candidate Robert Lowry defeated Benjamin King. The election was marred by massive fraud, and would mark the last time until 1975 that a candidate running against the official Democratic nominee received more than 40% of the vote.