The Mississippi Valley State Delta Devils basketball team represents Mississippi Valley State University in Itta Bena, Mississippi, in NCAA Division I competition. The school's team competes in the Southwestern Athletic Conference and plays home games in the Harrison HPER Complex.
The Delta Devils were most recently coached by George Ivory.
The Delta Devils have appeared in five NCAA tournaments. Their combined record is 0–5.
The Delta Devils have appeared in one National Invitation Tournament (NIT). Their record is 0–1.