The Miss Universo Paraguay 2012 pageant was held on May 18, 2012. Alba Riquelme, Miss Universo Paraguay 2011, crowned her successor Egny Eckert at the end of the event; she was the Paraguayan candidate for the 2012 Miss Universe pageant. Elected to represent Paraguay at Miss World 2012 was Fiorella Migiore, for Miss International 2012 was Nicole Huber, and for Miss Earth 2012 was Alexandra Fretes. The pageant was broadcast live on Telefuturo.
There were 7 official contestants.
The following persons judged the final competition.